Journal of International Pharmaceutical Research

Article: Impact of Home Pharmacy Care on Adherence of Chronic Renal Failure Patients Undergoing Hemodialysis in a Hospital in Indonesia

Pages: 308-312

Author: Deasy Nur Chairin Hanifa, Nanang Munif Yasin and Susi Ari Kristina

Abstract: One of the goals of home pharmacy care in patients with chronic renal failure is to improve adherence to taking medication. Renal failure is a chronic disease that requires long-term therapy. This research aimed to analyze the effectiveness of home pharmacy care on the adherence to taking medicine in chronic renal failure patients undergoing hemodialysis in a hospital in Indonesia. This research conducted using a quasi-experiment method with a one-group pretest-posttest design. Data took by consecutive sampling. The inclusion criteria were patients diagnosed with chronic renal failure who are undergoing hemodialysis with age over 18 years and could communicate well. Patients provided with a standard validated modified Medication Adherence Rating Scale questionnaire to assessing medication adherence before and after the intervention. This research conducted pharmacy service at home by giving one-time counseling, evaluation of drug use, and storage of drug for the patient of chronic renal failure undergoing hemodialysis. Data were analyzed using Paired sample T-Test and Wilcoxon test. The research respondents were 45 people. Statistical analysis of pretest and posttest data indicated that home pharmacy care improved patient adherence from average ± SD 6.62 ± 1.98 to 8.38 ± 1.58. Statistically, the significant association exists between medication adherence before and after the intervention (p <0.05). Counseling by pharmacists with booklet impact on patient's adherence to chronic renal failure undergoing hemodialysis.

Keywords: Counseling, Booklet, Chronic Renal Failure, Hemodialysis, Adherence