Treatment of minor recurrent aphthous ulceration through biostimulation mechanism by (650nm) diode laser

Abstract

Recurrent aphthous stomatitis is the commonest oral mucosal disorder all over the world, including Iraq, without a known
precise etiology or a specific efficacious therapy. Biostimulation with low level laser therapy was suggested as a safe,
alternative therapeutic option. A randomized patient-blinded placebo- controlled therapeutic study were conducted to
evaluate the efficacy and safety of low-power 650nm diode laser biostimulation in the management of patients with minor
recurrent aphthous ulcerations. The 15 patients completed the study were distributed randomly into three groups: the
placebo (A), lower dose laser (B) and higher dose laser (C) treated groups. Pain severity scores showed a comparable (and
almost similar) reduction in the two laser irradiated groups which was better than those for the sham irradiated group.
Reduction in the ulcers' sizes was most rapid in the higher dose laser group then the lower dose laser groups, and was least
in the placebo group. Finally, the higher dose laser group was faster to yield complete healing than lower dose laser group
which in turn showed shorter healing time than placebo treated group. Biostimulation of minor RAU using the (650 nm)
diode laser with the doses studied seems to be a safe and, effective treatment tool in management of minor RAUs.