Epidemiological and Immunological Study for Acute Amoebiasis Patients in Thi-Qar Governorate

Abstract

The present study aimed to find the relationship between Acute Amoebiasis and [Sex, Age and Location] in infected
patients, also to estimate the role of interleukine-12 [IL-12] and Tumor necrosis factor –alfa [TNF-α] in immune response
to Acute Amoebiasis patients by count the concentration of each one in study groups. Therefore, detected Acute infection
with Entamoeba histolytica caused Acute Amoebiasis and studying some of epidemiological [Sex, Age, Location] and
immunological [Cytokines IL12, TNF-α and Phagocytosis] parameters in infected patients. A total of [250] blood sample
were collected from patients have diarrhea from Thi-Qar hospitals and private laboratories, divided into [100] infected
samples with Acute Amoebiasis and [24] control from May 2018 to April 2019. The present study showed a relationship
between infection and age groups, for example, the maximum percentage of infection in the age group [1-10] years which
recorded 28% and the minimum percentage of infection in the age group [51-60] years which recorded 6%. The present
results were not significant between female and male. The infection according to location found significant increased of
percentage infection in rural area [68%]while decrease in urban area [32%].The present study showed significant
increasing in Interlukine-12 and Tummor necrosis factor-alfa [TNF-α] in infected group compared with control group.
Phagocytosis, the results showed increased significantly in the coefficient of phagocytosis in infected group compared with
control group.